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Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system

The M. tuberculosis (Mtb) ClpB is a protein disaggregase that helps to rejuvenate the bacterial cell. DnaK is a protein foldase that can function alone, but it can also bind to the ClpB hexamer to physically couple protein disaggregation with protein refolding, although the molecular mechanism is no...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Yin, Yanting, Feng, Xiang, Yu, Hongjun, Fay, Allison, Kovach, Amanda, Glickman, Michael S., Li, Huilin
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209680/
https://ncbi.nlm.nih.gov/pubmed/34038719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109166
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