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Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB.
We systematically analyzed the capability of the major cytosolic chaperones of Escherichia coli to cope with protein misfolding and aggregation during heat stress in vivo and in cell extracts. Under physiological heat stress conditions, only the DnaK system efficiently prevented the aggregation of t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171757/ https://ncbi.nlm.nih.gov/pubmed/10601016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.24.6934 |
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