Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia

TP53 mutations are strong predictors of poor survival and refractoriness in chronic lymphocytic leukemia (CLL) and have direct implications for disease management. Clinical information on TP53 mutations is limited to lesions represented in >20% leukemic cells. Here, we tested the clinical impact...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rossi, Davide, Khiabanian, Hossein, Spina, Valeria, Ciardullo, Carmela, Bruscaggin, Alessio, Famà, Rosella, Rasi, Silvia, Monti, Sara, Deambrogi, Clara, De Paoli, Lorenzo, Wang, Jiguang, Gattei, Valter, Guarini, Anna, Foà, Robin, Rabadan, Raul, Gaidano, Gianluca
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2014
Sujets:
Plenary Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017291/
https://ncbi.nlm.nih.gov/pubmed/24501221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-539726
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires