Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

The genetic lesions identified in chronic lymphocytic leukemia (CLL) do not entirely recapitulate the disease pathogenesis and the development of serious complications, such as chemorefractoriness. While investigating the coding genome of fludarabine-refractory CLL, we observed that mutations of SF3...

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Detalhes bibliográficos
Main Authors: Rossi, Davide, Bruscaggin, Alessio, Spina, Valeria, Rasi, Silvia, Khiabanian, Hossein, Messina, Monica, Fangazio, Marco, Vaisitti, Tiziana, Monti, Sara, Chiaretti, Sabina, Guarini, Anna, Del Giudice, Ilaria, Cerri, Michaela, Cresta, Stefania, Deambrogi, Clara, Gargiulo, Ernesto, Gattei, Valter, Forconi, Francesco, Bertoni, Francesco, Deaglio, Silvia, Rabadan, Raul, Pasqualucci, Laura, Foà, Robin, Dalla-Favera, Riccardo, Gaidano, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245210/
https://ncbi.nlm.nih.gov/pubmed/22039264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-373159
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