Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown. The full spectrum of genetic lesions that are present in the CLL genome, and therefore the number and identity of dysregulated cellular pathways, have not been identified. By combini...

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Autori principali: Fabbri, Giulia, Rasi, Silvia, Rossi, Davide, Trifonov, Vladimir, Khiabanian, Hossein, Ma, Jing, Grunn, Adina, Fangazio, Marco, Capello, Daniela, Monti, Sara, Cresta, Stefania, Gargiulo, Ernesto, Forconi, Francesco, Guarini, Anna, Arcaini, Luca, Paulli, Marco, Laurenti, Luca, Larocca, Luigi M., Marasca, Roberto, Gattei, Valter, Oscier, David, Bertoni, Francesco, Mullighan, Charles G., Foá, Robin, Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo, Gaidano, Gianluca
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135373/
https://ncbi.nlm.nih.gov/pubmed/21670202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110921
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