Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells

The ‘Yamanaka factors' (Oct4, Sox2, Klf4 and c-Myc) are able to generate induced pluripotent stem (iPS) cells from different cell types. However, to what degree primary malignant cells can be reprogrammed into a pluripotent state has not been vigorously assessed. We established an acute myeloid...

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Autors principals: Liu, Y, Cheng, H, Gao, S, Lu, X, He, F, Hu, L, Hou, D, Zou, Z, Li, Y, Zhang, H, Xu, J, Kang, L, Wang, Q, Yuan, W, Cheng, T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017259/
https://ncbi.nlm.nih.gov/pubmed/24150221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.304
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