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Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells
The ‘Yamanaka factors' (Oct4, Sox2, Klf4 and c-Myc) are able to generate induced pluripotent stem (iPS) cells from different cell types. However, to what degree primary malignant cells can be reprogrammed into a pluripotent state has not been vigorously assessed. We established an acute myeloid...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017259/ https://ncbi.nlm.nih.gov/pubmed/24150221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.304 |
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