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ERKed by LRRK2: A cell biological perspective on hereditary and sporadic Parkinson’s disease
The leucine rich repeat kinase 2 (LRRK2/dardarin) is implicated in autosomal dominant familial and sporadic Parkinson’s disease (PD); mutations in LRRK2 account for up to 40% of PD cases in some populations. LRRK2 is a large protein with a kinase domain, a GTPase domain, and multiple potential prote...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4016799/ https://ncbi.nlm.nih.gov/pubmed/24225420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.11.005 |
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