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Evolution of Tertiary Structure of Viral RNA Dependent Polymerases

Viral RNA dependent polymerases (vRdPs) are present in all RNA viruses; unfortunately, their sequence similarity is too low for phylogenetic studies. Nevertheless, vRdP protein structures are remarkably conserved. In this study, we used the structural similarity of vRdPs to reconstruct their evoluti...

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Autori principali: Černý, Jiří, Černá Bolfíková, Barbora, Valdés, James J., Grubhoffer, Libor, Růžek, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015915/
https://ncbi.nlm.nih.gov/pubmed/24816789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096070
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