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Origin and Evolution of RNA-Dependent RNA Polymerase

RNA-dependent RNA polymerases (RdRp) are very ancient enzymes and are essential for all viruses with RNA genomes. We reconstruct the origin and evolution of this polymerase since the initial stages of the origin of life. The origin of the RdRp was traced back from tRNA ancestors. At the origin of th...

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Dettagli Bibliografici
Pubblicato in:Front Genet
Autori principali: de Farias, Savio T., dos Santos Junior, Ariosvaldo P., Rêgo, Thais G., José, Marco V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611760/
https://ncbi.nlm.nih.gov/pubmed/28979293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00125
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