Skeletal Development of Mice Lacking Bone Sialoprotein (BSP) - Impairment of Long Bone Growth and Progressive Establishment of High Trabecular Bone Mass

Adult Ibsp-knockout mice (BSP−/−) display shorter stature, lower bone turnover and higher trabecular bone mass than wild type, the latter resulting from impaired bone resorption. Unexpectedly, BSP knockout also affects reproductive behavior, as female mice do not construct a proper "nest"...

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Main Authors: Bouleftour, Wafa, Boudiffa, Maya, Wade-Gueye, Ndeye Marième, Bouët, Guénaëlle, Cardelli, Marco, Laroche, Norbert, Vanden-Bossche, Arnaud, Thomas, Mireille, Bonnelye, Edith, Aubin, Jane E., Vico, Laurence, Lafage-Proust, Marie Hélène, Malaval, Luc
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015893/
https://ncbi.nlm.nih.gov/pubmed/24816232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095144
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