Skeletal Development of Mice Lacking Bone Sialoprotein (BSP) - Impairment of Long Bone Growth and Progressive Establishment of High Trabecular Bone Mass

Adult Ibsp-knockout mice (BSP−/−) display shorter stature, lower bone turnover and higher trabecular bone mass than wild type, the latter resulting from impaired bone resorption. Unexpectedly, BSP knockout also affects reproductive behavior, as female mice do not construct a proper "nest"...

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Hauptverfasser: Bouleftour, Wafa, Boudiffa, Maya, Wade-Gueye, Ndeye Marième, Bouët, Guénaëlle, Cardelli, Marco, Laroche, Norbert, Vanden-Bossche, Arnaud, Thomas, Mireille, Bonnelye, Edith, Aubin, Jane E., Vico, Laurence, Lafage-Proust, Marie Hélène, Malaval, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015893/
https://ncbi.nlm.nih.gov/pubmed/24816232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095144
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