Skeletal Development of Mice Lacking Bone Sialoprotein (BSP) - Impairment of Long Bone Growth and Progressive Establishment of High Trabecular Bone Mass

Adult Ibsp-knockout mice (BSP−/−) display shorter stature, lower bone turnover and higher trabecular bone mass than wild type, the latter resulting from impaired bone resorption. Unexpectedly, BSP knockout also affects reproductive behavior, as female mice do not construct a proper "nest"...

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Detalles Bibliográficos
Autores principales: Bouleftour, Wafa, Boudiffa, Maya, Wade-Gueye, Ndeye Marième, Bouët, Guénaëlle, Cardelli, Marco, Laroche, Norbert, Vanden-Bossche, Arnaud, Thomas, Mireille, Bonnelye, Edith, Aubin, Jane E., Vico, Laurence, Lafage-Proust, Marie Hélène, Malaval, Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015893/
https://ncbi.nlm.nih.gov/pubmed/24816232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095144
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