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Towards a facile and convenient synthesis of highly functionalized indole derivatives based on Multi-Component Reactions

A library of potentially bioactive compounds through the novel 1H-indole-methyl-isocyanide and MCRs has been described. A flexible and efficient synthesis affording great complexity and diversity is achieved, with moderate to good yields with no need for protection and deprotection steps.

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Bibliografiske detaljer
Main Authors: Neochoritis, Constantinos G., Dömling, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015188/
https://ncbi.nlm.nih.gov/pubmed/24477767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob00166d
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