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Towards a facile and convenient synthesis of highly functionalized indole derivatives based on Multi-Component Reactions
A library of potentially bioactive compounds through the novel 1H-indole-methyl-isocyanide and MCRs has been described. A flexible and efficient synthesis affording great complexity and diversity is achieved, with moderate to good yields with no need for protection and deprotection steps.
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015188/ https://ncbi.nlm.nih.gov/pubmed/24477767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob00166d |
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