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A multicomponent tetrazolo indole synthesis

The ubiquitous presence of the indole fragment in natural products and drugs asks for ever novel syntheses. We report an unprecedented mild, two-step synthesis of 2-tetrazolo substituted indoles based on the Ugi-tetrazole reaction combined with an acidic ring closure. A gram-scale synthesis, a bioac...

詳細記述

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書誌詳細
出版年:Chem Commun (Camb)
主要な著者: Lei, Xiaofang, Lampiri, Panagiota, Patil, Pravin, Angeli, Giasemi, Neochoritis, Constantinos G., Dömling, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society of Chemistry 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259579/
https://ncbi.nlm.nih.gov/pubmed/34128009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1cc02384e
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