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Extracellular Hb Enhances Cardiac Toxicity in Endotoxemic Guinea Pigs: Protective Role of Haptoglobin

Endotoxemia plays a major causative role in the myocardial injury and dysfunction associated with sepsis. Extracellular hemoglobin (Hb) has been shown to enhance the pathophysiology of endotoxemia. In the present study, we examined the myocardial pathophysiology in guinea pigs infused with lipopolys...

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Détails bibliographiques
Auteurs principaux: Baek, Jin Hyen, Zhang, Xiaoyuan, Williams, Matthew C., Schaer, Dominik J., Buehler, Paul W., D’Agnillo, Felice
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014731/
https://ncbi.nlm.nih.gov/pubmed/24691127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6041244
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