Extracellular Hb Enhances Cardiac Toxicity in Endotoxemic Guinea Pigs: Protective Role of Haptoglobin

Endotoxemia plays a major causative role in the myocardial injury and dysfunction associated with sepsis. Extracellular hemoglobin (Hb) has been shown to enhance the pathophysiology of endotoxemia. In the present study, we examined the myocardial pathophysiology in guinea pigs infused with lipopolys...

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Main Authors: Baek, Jin Hyen, Zhang, Xiaoyuan, Williams, Matthew C., Schaer, Dominik J., Buehler, Paul W., D’Agnillo, Felice
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014731/
https://ncbi.nlm.nih.gov/pubmed/24691127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6041244
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