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Blood-Brain Barrier Disruption and Oxidative Stress in Guinea Pig after Systemic Exposure to Modified Cell-Free Hemoglobin

Systemic exposure to cell-free hemoglobin (Hb) or its breakdown products after hemolysis or with the use of Hb-based oxygen therapeutics may alter the function and integrity of the blood-brain barrier. Using a guinea pig exchange transfusion model, we investigated the effect of a polymerized cell-fr...

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Auteurs principaux: Butt, Omer I., Buehler, Paul W., D'Agnillo, Felice
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069891/
https://ncbi.nlm.nih.gov/pubmed/21356382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.006
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