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Resistance to β-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica

Penicillin-binding proteins (PBPs) are enzymes responsible for the polymerization of the glycan strand and the cross-linking between glycan chains as well as the target proteins for β-lactam antibiotics. Mutational alterations in PBPs can confer resistance either by reducing binding of the antibioti...

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Main Authors: Sun, Song, Selmer, Maria, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014608/
https://ncbi.nlm.nih.gov/pubmed/24810745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097202
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