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Improved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases

Triplex structures generated by sequence-specific triplex-forming oligonucleotides (TFOs) have proven to be promising tools for gene targeting strategies. In addition, triplex technology has been highly utilized to study the molecular mechanisms of DNA repair, recombination and mutagenesis. However,...

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Bibliografiske detaljer
Main Authors: Rogers, Faye A, Lloyd, Janice A, Tiwari, Meetu Kaushik
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014521/
https://ncbi.nlm.nih.gov/pubmed/25483840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.27792
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