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Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides

Triplex-forming oligonucleotides (TFOs) are DNA-binding molecules, which offer the potential to selectively modulate gene expression. However, the biological activity of TFOs as potential antigene compounds has been limited by cellular uptake. Here, we investigate the effect of cell-penetrating pept...

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Détails bibliographiques
Auteurs principaux: Rogers, Faye A., Manoharan, Muthiah, Rabinovitch, Peter, Ward, David C., Glazer, Peter M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC545466/
https://ncbi.nlm.nih.gov/pubmed/15602001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh998
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