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Improved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases

Triplex structures generated by sequence-specific triplex-forming oligonucleotides (TFOs) have proven to be promising tools for gene targeting strategies. In addition, triplex technology has been highly utilized to study the molecular mechanisms of DNA repair, recombination and mutagenesis. However,...

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Detalles Bibliográficos
Main Authors: Rogers, Faye A, Lloyd, Janice A, Tiwari, Meetu Kaushik
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014521/
https://ncbi.nlm.nih.gov/pubmed/25483840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.27792
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