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Paternal Poly (ADP-ribose) Metabolism Modulates Retention of Inheritable Sperm Histones and Early Embryonic Gene Expression

To achieve the extreme nuclear condensation necessary for sperm function, most histones are replaced with protamines during spermiogenesis in mammals. Mature sperm retain only a small fraction of nucleosomes, which are, in part, enriched on gene regulatory sequences, and recent findings suggest that...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ihara, Motomasa, Meyer-Ficca, Mirella L., Leu, N. Adrian, Rao, Shilpa, Li, Fan, Gregory, Brian D., Zalenskaya, Irina A., Schultz, Richard M., Meyer, Ralph G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014456/
https://ncbi.nlm.nih.gov/pubmed/24810616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004317
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