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Mlh2 Is an Accessory Factor for DNA Mismatch Repair in Saccharomyces cerevisiae
In Saccharomyces cerevisiae, the essential mismatch repair (MMR) endonuclease Mlh1-Pms1 forms foci promoted by Msh2-Msh6 or Msh2-Msh3 in response to mispaired bases. Here we analyzed the Mlh1-Mlh2 complex, whose role in MMR has been unclear. Mlh1-Mlh2 formed foci that often colocalized with and had...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014439/ https://ncbi.nlm.nih.gov/pubmed/24811092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004327 |
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