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Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System

Previous studies reported the reconstitution of an Mlh1-Pms1-independent 5′ nick-directed mismatch repair (MMR) reaction using Saccharomyces cerevisiae proteins. Here we describe the reconstitution of a mispair-dependent Mlh1-Pms1 endonuclease activation reaction requiring Msh2-Msh6 (or Msh2-Msh3),...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Smith, Catherine E., Bowen, Nikki, Graham, William J., Goellner, Eva M., Srivatsan, Anjana, Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571882/
https://ncbi.nlm.nih.gov/pubmed/26170454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662189
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