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Mispair-specific Recruitment of the Mlh1-Pms1 Complex Identifies Repair Substrates of the Saccharomyces cerevisiae Msh2-Msh3 Complex

DNA mismatch repair is initiated by either the Msh2-Msh6 or the Msh2-Msh3 mispair recognition heterodimer. Here we optimized the expression and purification of Saccharomyces cerevisiae Msh2-Msh3 and performed a comparative study of Msh2-Msh3 and Msh2-Msh6 for mispair binding, sliding clamp formation...

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Detalhes bibliográficos
Main Authors: Srivatsan, Anjana, Bowen, Nikki, Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979400/
https://ncbi.nlm.nih.gov/pubmed/24550389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552190
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