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Impact of drug size on brain tumor and brain parenchyma delivery after a blood–brain barrier disruption

Drug delivery to the brain is influenced by the blood–brain barrier (BBB) and blood–tumor barrier (BTB) to an extent that is still debated in neuro-oncology. In this paper, we studied the delivery across the BTB and the BBB of compounds with different molecular sizes in normal and glioma-bearing rat...

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Detalhes bibliográficos
Main Authors: Blanchette, Marie, Tremblay, Luc, Lepage, Martin, Fortin, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013755/
https://ncbi.nlm.nih.gov/pubmed/24517973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.14
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