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Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

Therapeutic interventions based on metabolic inhibitor-based therapies are expected to be less prone to acquired resistance. However, there has not been any study assessing the possibility that the targeting of the tumor cell metabolism may result in unforeseeable resistance. We recently established...

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Autors principals: Oliveras-Ferraros, Cristina, Vazquez-Martin, Alejandro, Cuyàs, Elisabet, Corominas-Faja, Bruna, Rodríguez-Gallego, Esther, Fernández-Arroyo, Salvador, Martin-Castillo, Begoña, Joven, Jorge, Menendez, Javier A
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013163/
https://ncbi.nlm.nih.gov/pubmed/24553122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27982
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