Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile

Therapeutic interventions based on metabolic inhibitor-based therapies are expected to be less prone to acquired resistance. However, there has not been any study assessing the possibility that the targeting of the tumor cell metabolism may result in unforeseeable resistance. We recently established...

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Detaylı Bibliyografya
Asıl Yazarlar: Oliveras-Ferraros, Cristina, Vazquez-Martin, Alejandro, Cuyàs, Elisabet, Corominas-Faja, Bruna, Rodríguez-Gallego, Esther, Fernández-Arroyo, Salvador, Martin-Castillo, Begoña, Joven, Jorge, Menendez, Javier A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013163/
https://ncbi.nlm.nih.gov/pubmed/24553122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27982
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