Novel Interaction of Ornithine Decarboxylase with Sepiapterin Reductase Regulates Neuroblastoma Cell Proliferation

Ornithine decarboxylase (ODC) is the sentinel enzyme in polyamine biosynthesis. Both ODC and polyamines regulate cell division, proliferation, and apoptosis. Sepiapterin reductase (SPR) catalyzes the last step in the biosynthesis of tetrahydrobiopterin (BH(4)), an essential cofactor of nitric oxide...

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Bibliografiske detaljer
Main Authors: Lange, Ingo, Geerts, Dirk, Feith, David J., Mocz, Gabor, Koster, Jan, Bachmann, André S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013099/
https://ncbi.nlm.nih.gov/pubmed/24096079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.09.037
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