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Targeting Ornithine Decarboxylase Impairs Development of MYCN-Amplified Neuroblastoma

Neuroblastoma is a pediatric malignancy that arises from the neural crest and patients with high-risk neuroblastoma that typically harbor amplifications of MYCN have an extremely poor prognosis. The tyrosine hydroxylase (TH) promoter-driven TH-MYCN transgenic mouse model faithfully recapitulates man...

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Detalhes bibliográficos
Main Authors: Rounbehler, Robert J., Li, Weimin, Hall, Mark A., Yang, Chunying, Fallahi, Mohammad, Cleveland, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749594/
https://ncbi.nlm.nih.gov/pubmed/19147568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2968
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