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DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27(Kip1) activity in neuroblastoma

Neuroblastoma (NB) is the most common extracranial pediatric tumor. NB patients over 18 months of age at the time of diagnosis are often in the later stages of the disease, present with widespread dissemination, and often possess MYCN tumor gene amplification. MYCN is a transcription factor that reg...

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書誌詳細
主要な著者: KOOMOA, DANA-LYNN T., GEERTS, DIRK, LANGE, INGO, KOSTER, JAN, PEGG, ANTHONY E., FEITH, DAVID J., BACHMANN, ANDRÉ S.
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622674/
https://ncbi.nlm.nih.gov/pubmed/23440295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.1835
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