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MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines

Neuroblastoma is an extra-cranial solid cancer in children. MYCN gene amplification is a prognostic indicator of poor outcome in neuroblastoma. Recent studies have shown that the multiple steps involved in cell migration are dependent on the availability of intracellular calcium (Ca(2+)). Although s...

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Publicat a:FEBS Open Bio
Autors principals: Lange, Ingo, Koomoa, Dana-Lynn T.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241534/
https://ncbi.nlm.nih.gov/pubmed/25426416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.10.012
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