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The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification
High polyamine (PA) levels and ornithine decarboxylase (ODC) over-expression are well-known phenomena in many aggressive cancer types. We analyzed the expression of ODC and ODC-activity regulating genes antizymes 1-3 (OAZ1-3) and AZ inhibitors 1-2 (AZ-IN1-2) in human neuroblastoma (NB) tumors and co...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847573/ https://ncbi.nlm.nih.gov/pubmed/19960435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25074 |
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