Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells

AIM: To determine the effects and potential mechanisms of ibrolipim on ATP-binding membrane cassette transporter A-1 (ABCA1) and ATP-binding membrane cassette transporter G-1 (ABCG1) expression from human macrophage foam cells, which may play a critical role in atherogenesis. METHODS: Human THP-1 ce...

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Autors principals: Chen, Si-guo, Xiao, Ji, Liu, Xie-hong, Liu, Mei-mei, Mo, Zhong-cheng, Yin, Kai, Zhao, Guo-jun, Jiang, Jin, Cui, Li-bao, Tan, Chun-zhi, Yin, Wei-dong, Tang, Chao-ke
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012897/
https://ncbi.nlm.nih.gov/pubmed/20871621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.166
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