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Design, Synthesis and Biological Evaluation of Tasiamide Analogues as Tumor Inhibitors

Eighteen analogues of the marine cytotoxic linear peptide tasiamide were designed, synthesized and screened for their inhibitory activities against the growth of human nasopharyngeal carcinoma (KB) and human non-small cell lung tumor (A549) cell lines. The results indicated that minor modifications...

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Bibliografiske detaljer
Main Authors: Zhang, Wei, Sun, Tiantian, Ma, Zhenhua, Li, Yingxia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012464/
https://ncbi.nlm.nih.gov/pubmed/24759000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12042308
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