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Design, synthesis and biological evaluation of selective survivin inhibitors

The differential distribution between cancer cells and normal adult tissues makes survivin a very attractive cancer drug target. We have previously reported a series of novel selective survivin inhibitors with the most potent compound MX106 reaching nanomolar activity in several cancer cell lines. F...

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Dades bibliogràfiques
Publicat a:J Biomed Res
Autors principals: Xiao, Min, Xue, Yi, Wu, Zhongzhi, Lei, Zi-Ning, Wang, Jin, Chen, Zhe-Sheng, Li, Wei
Format: Artigo
Idioma:Inglês
Publicat: Editorial Department of Journal of Biomedical Research 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477172/
https://ncbi.nlm.nih.gov/pubmed/30174320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.31.20160173
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