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Design, Synthesis and Biological Evaluation of Tasiamide Analogues as Tumor Inhibitors

Eighteen analogues of the marine cytotoxic linear peptide tasiamide were designed, synthesized and screened for their inhibitory activities against the growth of human nasopharyngeal carcinoma (KB) and human non-small cell lung tumor (A549) cell lines. The results indicated that minor modifications...

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Hlavní autoři: Zhang, Wei, Sun, Tiantian, Ma, Zhenhua, Li, Yingxia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012464/
https://ncbi.nlm.nih.gov/pubmed/24759000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12042308
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