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THE ANTI-MELANOMA ACTIVITY OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT (LBH589) IS MEDIATED BY DIRECT TUMOR CYTOTOXICITY AND INCREASED TUMOR IMMUNOGENICITY
OBJECTIVES: Melanoma is the deadliest skin cancer, and its incidence has been increasing faster than any other cancer. Although immunogenic, melanoma is not effectively cleared by host immunity. In this study, we investigate the therapeutic, anti-melanoma potential of the histone deacetylase inhibit...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012016/ https://ncbi.nlm.nih.gov/pubmed/23963286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e328364c0ed |
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