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Influence of glycosylation pattern on the molecular properties of monoclonal antibodies

Glycosylation is an important post-translational modification during protein production in eukaryotic cells, and it is essential for protein structure, stability, half-life, and biological functions. In this study, we produced various monoclonal antibody (mAb) glycoforms from Chinese hamster ovary (...

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Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Kai, Yarmarkovich, Mark, Bantog, Christopher, Bayer, Robert, Patapoff, Thomas W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011909/
https://ncbi.nlm.nih.gov/pubmed/24662970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.28588
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