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Influence of glycosylation pattern on the molecular properties of monoclonal antibodies
Glycosylation is an important post-translational modification during protein production in eukaryotic cells, and it is essential for protein structure, stability, half-life, and biological functions. In this study, we produced various monoclonal antibody (mAb) glycoforms from Chinese hamster ovary (...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011909/ https://ncbi.nlm.nih.gov/pubmed/24662970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.28588 |
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