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Apurinic/Apyrimidinic Endonucleases of Mycobacterium tuberculosis Protect against DNA Damage but Are Dispensable for the Growth of the Pathogen in Guinea Pigs

In host cells, Mycobacterium tuberculosis encounters an array of reactive molecules capable of damaging its genome. Non-bulky DNA lesions are the most common damages produced on the exposure of the pathogen to reactive species and base excision repair (BER) pathway is involved in the repair of such...

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Bibliografske podrobnosti
Main Authors: Puri, Rupangi Verma, Reddy, P. Vineel, Tyagi, Anil K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011885/
https://ncbi.nlm.nih.gov/pubmed/24800740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092035
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