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Endonuclease IV Is the Major Apurinic/Apyrimidinic Endonuclease in Mycobacterium tuberculosis and Is Important for Protection against Oxidative Damage

During the establishment of an infection, bacterial pathogens encounter oxidative stress resulting in the production of DNA lesions. Majority of these lesions are repaired by base excision repair (BER) pathway. Amongst these, abasic sites are the most frequent lesions in DNA. Class II apurinic/apyri...

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Detalhes bibliográficos
Main Authors: Puri, Rupangi Verma, Singh, Nisha, Gupta, Rakesh K., Tyagi, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731287/
https://ncbi.nlm.nih.gov/pubmed/23936515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071535
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