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Apurinic/Apyrimidinic Endonucleases of Mycobacterium tuberculosis Protect against DNA Damage but Are Dispensable for the Growth of the Pathogen in Guinea Pigs

In host cells, Mycobacterium tuberculosis encounters an array of reactive molecules capable of damaging its genome. Non-bulky DNA lesions are the most common damages produced on the exposure of the pathogen to reactive species and base excision repair (BER) pathway is involved in the repair of such...

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Detalhes bibliográficos
Main Authors: Puri, Rupangi Verma, Reddy, P. Vineel, Tyagi, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011885/
https://ncbi.nlm.nih.gov/pubmed/24800740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092035
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