LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer

The Leucine Zipper Tumor Suppressor 1 (LZTS1) is a tumor suppressor gene, located at chromosome 8p22, which is frequently altered in human cancer. In normal tissue, its ubiquitous expression regulates cell mitosis by the stabilization of microtubule networks. LZTS1-deficient mouse embryonic fibrobla...

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Autori principali: Lovat, Francesca, Ishii, Hideshi, Schiappacassi, Monica, Fassan, Matteo, Barbareschi, Mattia, Galligioni, Enzo, Gasparini, Pierluigi, Baldassarre, Gustavo, Croce, Carlo M., Vecchione, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011598/
https://ncbi.nlm.nih.gov/pubmed/24448468
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