FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis

The FEZ1/LZTS1 gene maps to chromosome 8p22, a region that is frequently deleted in human tumors. Alterations in FEZ1/LZTS1 expression have been observed in esophageal, breast, and prostate cancers. Here, we show that introduction of FEZ1/LZTS1 into Fez1/Lzts1-negative cancer cells results in suppre...

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Bibliographic Details
Main Authors: Ishii, Hideshi, Vecchione, Andrea, Murakumo, Yoshiki, Baldassarre, Gustavo, Numata, Shinichiro, Trapasso, Francesco, Alder, Hansjuerg, Baffa, Raffaele, Croce, Carlo M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC56968/
https://ncbi.nlm.nih.gov/pubmed/11504921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181222898
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