FEZ1/LZTS1 Is Down-Regulated in High-Grade Bladder Cancer, and Its Restoration Suppresses Tumorigenicity in Transitional Cell Carcinoma Cells

FEZ1/LZTS1 is a tumor suppressor gene that maps to chromosome 8p22, a chromosomal region frequently deleted in many human malignancies, including transitional cell carcinoma (TCC) of the urinary bladder. FEZ1/LZTS1 alterations have been reported in esophageal, breast, prostate, and gastric carcinoma...

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Detalhes bibliográficos
Main Authors: Vecchione, Andrea, Ishii, Hideshi, Baldassarre, Gustavo, Bassi, Pierfrancesco, Trapasso, Francesco, Alder, Hansjuerg, Pagano, Francesco, Gomella, Leonard G., Croce, Carlo M., Baffa, Raffaele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867220/
https://ncbi.nlm.nih.gov/pubmed/11943719
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