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Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells
In this study we demonstrate a new form of immunoregulation: engagement on CD4(+) T cells of the complement regulator CD46 promoted the effector potential of T helper type 1 cells (T(H)1 cells), but as interleukin 2 (IL-2) accumulated, it switched cells toward a regulatory phenotype, attenuating IL-...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011020/ https://ncbi.nlm.nih.gov/pubmed/20694009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1917 |
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