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CD46 in innate and adaptive immunity: an update
CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that defi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3087925/ https://ncbi.nlm.nih.gov/pubmed/21488871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04400.x |
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