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Formulation development for the orexin receptor antagonist almorexant: assessment in two clinical studies
Almorexant, a dual orexin receptor antagonist, was investigated for the treatment of insomnia. The following observations initiated further formulation development: the active pharmaceutical ingredient (API) was sticking to the apparatus used during tablet compression; almorexant has an absolute bio...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010641/ https://ncbi.nlm.nih.gov/pubmed/24812492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S62118 |
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